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By Dr. Jennifer Thompson, DVM, Board-Certified Veterinary Dermatologist

Last reviewed: February 13, 2026

Skin Cytology in Dogs: What to Expect

Skin cytology is a rapid, non-invasive diagnostic test that helps veterinarians identify infections and other skin conditions. Learn what this procedure involves.

Written by Sarah Mitchell, Veterinary Content Specialist
Published February 13, 2024
6 min read

Veterinary Medical Disclaimer

This information is provided for educational purposes and is not intended to replace professional veterinary advice, diagnosis, or treatment. Always seek the advice of your veterinarian with any questions you may have regarding your pet's medical condition. Never disregard professional veterinary advice or delay in seeking it because of something you have read on this website.

What is Skin Cytology?

Skin cytology is a microscopic examination of cells and organisms from your dog's skin. It's one of the most valuable and frequently used diagnostic tests in veterinary dermatology, providing rapid information about infections and inflammatory conditions.

Why It's Performed

Skin cytology helps identify:

  • Bacterial infections
  • Yeast infections
  • Types of inflammatory cells present
  • Presence of mites or other parasites
  • Abnormal cells suggesting other conditions

Sample Collection Methods

Impression Smears

Glass slide pressed directly against moist lesions or skin surface

Tape Preparations

Clear tape pressed against skin to collect surface material

Cotton Swabs

Swab rolled across lesions or within ear canals

Fine Needle Aspirate

Small needle used to collect cells from lumps or nodules

What to Expect

  • Quick and simple: Takes only a few minutes
  • Minimally invasive: Usually painless
  • No sedation needed: Most dogs tolerate well
  • Rapid results: Often available during same appointment
  • Affordable: One of the most cost-effective diagnostics

What Results Mean

Your veterinarian will examine samples under microscope and look for specific findings that guide treatment decisions. Results help determine appropriate medications and monitor treatment response.

Follow-Up Cytology

Repeat cytology during treatment confirms infection resolution and helps determine when therapy can be stopped safely.

Key Points

  • Skin cytology is quick, simple, and informative
  • Helps identify infections and guide treatment
  • Essential for monitoring treatment progress
  • Well-tolerated by most dogs
  • Cost-effective diagnostic tool